| GCRC # |
Protocol Title |
Primary Investigator |
GCRC Approval Date |
| 0003 | Brain Aging Project: Energy Metabolism and Brain Changes With Age and Alzheimer's Disease | Jeffery Burns, MD | Sep 29, 2004 |
| 0006 | Sex Differences in Autism: Potential Role of Oxytocin Signaling | Kathryn Ellerbeck, MD | Oct 27, 2004 |
| 0010 | Pharmacokinetic Evaluation of Intravenous Vitamin C | Jeanne Drisko, MD | Aug 22, 2007 |
| 0016 | Prospective Huntington At Risk Observational Study | Richard Dubinsky, MD,MPH | Mar 30, 2005 |
| 0020 | Alzheimer's Disease Neuroimaging Initiative | Jeffery Burns, MD | May 25, 2005 |
| 0024 | Double Blind Placebo Controlled Evaluation of Bioidentical Hormones | Jeanne Drisko, MD | Nov 30, 2005 |
| 0027 | A Multi-Center, Double-Blind, Randomized Study Comparing the Combined Use of Interferon Beta-1a and Glatiramir Acetate to Either Agent Alone in Patients with Relapsing Remitting Multiple Sclerosis (CombiRx-Phase III) | Sharon Lynch, MD | Aug 24, 2005 |
| 0034 | Cutaneous innervation in human diabetic neuropathy | Mamatha Pasnoor, MD | Sep 28, 2005 |
| 0038 | A Phase 2, Multi-center, Open-label Study to Determine Long-term Safety, Tolerability and Efficacy of Split-dose Oral Regimens of Tolvaptan Tablets in a Range of 30 to 120 mg/d in Patients with Autosomal Dominant Polycystic Kidney Disease
| Franz Winklhofer, MD | Oct 26, 2005 |
| 0039 | HALT PKD (Halt Progression of Polycystic Kidney Disease)
Efficacy of Aggressive Renin-Angiotensin-Aldosterone Axis Blockade
in Preventing/Slowing Renal Function Decline in ADPKD
| Franz Winklhofer, MD | Nov 30, 2005 |
| 0043 | Clinical Investigation of Neurological Channelopathies”(CINCH)
Nondystrophic Myotonias( NDM)
| Richard J Barohn, MD | Nov 30, 2005 |
| 0045 | A Double-Blind, Placebo-Control Trial of Etanercept in Dermatomyositis | Richard Barohn, MD | date not assigned |
| 0048 | Cooperative Huntington's Obervational Research Trial | Richard Dubinsky, MD, MPH | Apr 26, 2006 |
| 0049 | Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM) | Richard Barohn, MD | date not assigned |
| 0052 | Disease Management For Smokers in Rural Primary Care | Edward Ellerbeck, MD, MPH | date not assigned |
| 0054 | A randomized execise trial for wheelchair users | Katherine Froehlich-Grobe, PhD | Jun 28, 2006 |
| 0056 | Bi-axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Peripheral Neuropathy: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial | Mamatha Pasnoor, MD | Jul 26, 2006 |
| 0061 | A Multi-Center, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone. | Richard J Barohn, MD | Oct 25, 2006 |
| 0062 | A Phase 3, Multi-center, Double-blind, Placebo-controlled, Parallel-arm Trial to Determine Long-term Safety and Efficacy of an Oral study drug Regimens in Adult Subjects with Autosomal Dominant Polycystic Kidney Disease | Franz Winklhofer, MD | Oct 25, 2006 |
| 0063 | A Randomized, Double-Blind, Placebo-Controlled Trial of the Effects of Docosahexaenoic Acid(DHA) in Slowing the Progression of Alzheimer's Disease
| Jeffrey M. Burns, MD | Nov 29, 2006 |
| 0065 | A Randomized, Double-Blind, Multicenter, Multinational, Placebo-Controlled Study of the Safety, Efficacy, and Pharmacokinetics of Myozyme, Recombinant Human Acid alpha-Glucosidase (rhGAA), Treatment in Patients with Late-Onset Pompe Disease | Richard Barohn, MD | Nov 29, 2006 |
| 0066 | Episodic Ataxia Syndrome: Genotype-phenotype correlation and longitudinal study. | Richard Barohn, MD | Nov 29, 2006 |
| 0069 | Consortium for Radiologic Imaging Studies of Polycystic Kidney Diesase (CRISP II) | Jared Grantham, MD | Mar 21, 2007 |
| 0070 | Dichlorphenamide Vs. Acetazolamide for Periodic Paralysis | Richard Barohn, MD | Mar 21, 2007 |
| 0073 | Neuroimaging Marker of Amyotrophic Lateral Sclerosis | Yunxia Wang, MD | Jun 28, 2007 |
| 0074 | Enhancing Nutrition and Activity in Rural Children: The Healthy Schools Project | Ann McGrath Davis, MD | Apr 25, 2007 |
| 0075 | Intranasal Insulin and Memory in Early Alzheimer’s Disease | Jeffrey M. Burns, MD | May 8, 2007 |
| 0080 | Arimoclomol for Sporadic Inclusion Body Myositis (FDA IND #76,773) | Richard Barohn, MD | Jul 25, 2007 |
| 0082 | Hyperglycemia and oxidative stress in the human brain with diabetes | In-Young Choi | Aug 22, 2007 |
| 0083 | Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients | Rajib Bhattacharya, MD | Sep 26, 2007 |
| 0084 | Therapeutic Trial of Mexiletine in Non-Dystrophic Myotonia (IND #77,021) | Yunxia Wang, MD | Oct 29, 2007 |
| 0085 | Alzheimer and Memory Program Registry | Jeffrey M. Burns, MD | Oct 12, 2007 |
| 0091 | Clinical Trial of Ceftriaxone in Subjects with ALS | Richard Barohn, MD | date not assigned |
| 0092 | A PHASE 1B, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE SAFETY OF MULTIPLE-DOSE, INTRAVENOUSLY ADMINISTERED MEDI-545, A FULLY HUMAN ANTI-INTERFERON-ALPHA MONOCLONAL ANTIBODY, IN ADULT PATIENTS WITH DERMATOMYOSITIS OR POLYMYOSITIS | Mazen Dimachkie, MD | May 19, 2008 |
| 0093 | 301-A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled., Paralled-Group, Efficacy and Safety Trial of Bapineuzumab(AAB-001, Elan115727)in Patients with Mild to Moderate Alzheimer's Disease who are Aplolipoprotein Ee 4 Non-carriers | Jeffrey M. Burns | May 14, 2008 |
| 0094 | 302-A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Paralled-Group, Efficacy and Safety Trial of Bapineuzumab (AAB-001, Elan115727) in Patients with Mild to Moderate Alzheimer's Disease who are Aplolipoprotein Ee 4 Carriers | Jeffrey Burns, MD | May 14, 2008 |
| 0095 | The Effectiveness of Benfotiamine in Reducing Abusive Drinking among Family History Positive and Negative Alcoholics | Ann M. Manzardo, Ph.D. | Mar 4, 2008 |
| 0096 | A Phase II, Double Blind, Randomized, Placebo Controlled, Multi-Center, Dose Ranging, Parallel-Group, Study to Evaluate the Safety and Efficacy of Oral ELND005 (AZD-103) in Patients with Mild to Moderate Alzheimer’s Disease | Jeffrey M. Burns,MS | Feb 27, 2008 |
| 0097 | A Phase 2b Efficacy and Safety Study of PTC124 in Subjects with Nonsense-Mutation-Mediated Duchenne and Becker Muscular Dystrophy | Richard Barohn, MD | Mar 26, 2008 |
| 0098 | Co-Enzyme Q10 in Huntington's Disease (HD) 2-CARE | Richard Dubinsky,MD, MPH | Feb 27, 2008 |
| 0099 | Precision Assessment of DXA Bone Mineral Density and Total Body Fat Percentage Testing | Patricia Kluding | Mar 4, 2008 |
| 0100 | A Randomized Phase IIb Placebo-controlled Study of R-ICE Chemotherapy (Rituximab, Ifosfamide, Carboplatin, and Etoposide) with and without SGN-40 (anti-CD40 humanized monoclonal antibody) for Second-line Treatment of Patients with Diffuse Large B-Cell Lymphoma (DLBCL) | Delva Deauna-Limayo | Mar 26, 2008 |
| 0101 | Andersen-Tawil Syndrome: Genotype-phenotype correlation and longitudinal study | Richard J. Barohn, MD | Mar 26, 2008 |
| 0102 | The Body’s Response to Food Intake in Adolescents | Heather Leidy, PhD | Mar 26, 2008 |
| 0103 | Phase II Trial of methotrexate in myashtenia gravis | Richard J. Barohn, MD | Sep 23, 2008 |
| 0104 | An Open-Label Pilot Study of the Safety, Tolerability and Anti-Viral Activity of High Dose Intravenous Ascorbic Acid (HDIVAA) in Patients Chronically Infected with Hepatitis C Virus (HCV) genotype 1, who have Failed Prior Therapy with Interferon-alpha and Ribavirin. | Jeanne Drisko, MD and Richard Gilroy, MD | Jul 23, 2008 |
| 0105 | Pilot Study of Exercise and Peripheral Nerve Function in People with Diabetes | Patricia Kluding | Apr 23, 2008 |
| 0109 | Insulin and Brain Atrophy in Parkinson’s and Parkinson’s Disease Dementia | Jeffrey M. Burns | May 28, 2008 |
| 0110 | An Open-label, Feasibility Study of Peripheral Sympathetic Nerve Stimulation (PSNS) for Weight Reduction in Obese Patients | Richard McCallum, MD | Dec 11, 2008 |
| 0111 | Brain Function Predictors and Outcome of Weight Loss and Weight Loss Maintenance | Cary R Savage, Ph.D. | Jul 23, 2008 |
| 0112 | Osteopenia in patients with Autosomal Dominant Polycystic Kidney Disease | James B Wetmore | Jul 23, 2008 |
| 0113 | A Pilot Test of Healthy Hawks Super | Ann M Davis PhD MPH | Aug 27, 2008 |
| 0114 | Fibromyalgia and Sleep Treatment (Project FAST) | Nancy A. Hamilton | Aug 29, 2008 |
| 0115 | Studies of Genes and Energy Metabolism in Aging and Neurology Disorders | Russell Swerdlow, MD | Oct 22, 2008 |
| 0116 | C08: 001: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, CROSS-OVER, MULTI-CENTER STUDY OF ECULIZUMAB IN PATIENTS WITH GENERALIZED MYASTHENIA GRAVIS (GMG) WHO HAVE MODERATE TO SEVERE MUSCLE WEAKNESS DESPITE TREATMENT WITH IMMUNOSUPPRESSANTS | Richard Barohn, M.D | Oct 22, 2008 |
| 0118 | Alternative Options to Minimize Niacin-Induces Flushing-A Pilot Study | Patrick M. Moriarty, MD | Nov 19, 2008 |
| 0119 | Impact of Vitamin D Supplementation on Lactation Associated Bone Loss | Leigh M. Eck, MD | Nov 19, 2008 |
| 0120 | A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, TWO DOSE-ARM, PARALLEL STUDY OF THE SAFETY AND EFFECTIVENESS OF IMMUNE GLOBULIN INTRAVENOUS (HUMAN), 10% (IGIV, 10%) FOR THE TREATMENT OF MILD-TO-MODERATE ALZHEIMER’S DISEASE [THE GAMMAGLOBULIN LIQUID FOR ALHEIMER'S DISEASE (GLAD) TRIAL] | Jeffrey M. Burns, MD | Nov 19, 2008 |
| 0121 | Prader-Willi Syndrome and Early-Onset Morbid Obesity Natural History Clinical Protocol | Merlin G. Butler, M.D., Ph.D. | Apr 22, 2009 |
| 0122 | Fall Risk Assessment in People with Diabetic Neuropathy | Stephen Jernigan | Jan 28, 2009 |
| 0124 | Creatine Safety, Tolerability, and Efficacy in Huntington's Disease (CREST-E) | Richard Dublinsky, MD | Apr 22, 2009 |
| 0125 | A Combination Trial of Copaxone plus Estriol in Relapsing Remitting Multiple Sclerosis. | Dr. Sharon Lynch | Apr 22, 2009 |
| 0127 | Hormones and DNA Methylation in Autism | Kathryn Ellerbeck, MD, MPH | May 27, 2009 |
| 0128 | Fitness and Executive Function in Early Alzheimer's Disease | Jeff Burns | May 27, 2009 |
| 0129 | Genetic factors affecting susceptibility to diabetic retinopathy in type I diabetes mellitus | Robert Charles Andrew Symons, MD, PhD | May 27, 2009 |
| 0130 | Pilot study relating lifestyle factors to Physical and Cognitive Health in Elderly American Indian Population | Heather Anderson, MD | May 27, 2009 |
| 0131 | TELEMEDICINE FOR SMOKING CESSATION IN RURAL PRIMARY CARE | Kimber Richter, PhD | Jun 24, 2009 |
| 0132 | Efficacy of Once Weekly Atorvastatin or Rosuvastatin - A Pilot Study | James M. Backes | Jun 24, 2009 |
| 0133 | Assessment of Automatic and Attention-Modulated Sensorimotor Gating in Attention Deficit-Hyperactivity Disorder (ADHD) | Poje, Albert B | Jun 24, 2009 |
| 0134 | Multi-Center ALS Cohort Study of Oxidative Stress and Disease Progression | Richard Barohn, M.D | Aug 26, 2009 |
| 0135 | A Multi-Center Controlled Screening Trial of Safety and Efficacy of Rasagiline in Subjects with Amyotrophic Lateral Sclerosis (ALS)
| Yunxia Wang, M.D. | Jul 22, 2009 |
| 0136 | The Health Benefits of Breakfast | Heather J. Leidy | Jul 22, 2009 |
| 0138 | Trail of Exercise on Aging and Memory (TEAM) Study | Jeffrey M. Burns, MD | Jul 22, 2009 |
| 0139 | A Randomized Controlled Trial to Enhance Nutrition and Activity Among Rural Children | Ann McGrath Davis, Ph.D. | Aug 26, 2009 |
| 0140 | Factors associated with functional recovery post-stroke | Barbara Quaney, PT, PhD | Aug 26, 2009 |
| 0141 | Supervised Exercise Program in Early Alzheimer's Disease (ADEPT) | Jeffrey M. Burn, MD | Aug 26, 2009 |
| 0142 | Resistance Training with Milk Supplementation in Adolescents | Joseph E. Donnelly | Aug 26, 2009 |
| 0143 | An Observational Study of the Clinical and Virologic Manifestations of Novel and Seasonal Influenza
| Lisa Clough, MD | Oct 28, 2009 |